the synthesis of a water-soluble derivative of rutin as an antiradical agent</h1> <div class="paper-metrics"> <div class="paper-metric"> <i class="fas fa-eye"></i> Clicks: 78 </div> <div class="paper-metric"> <i class="fas fa-hashtag"></i> ID: 158007 </div> <div class="paper-metric"> <i class="fas fa-calendar-alt"></i> 2008 </div> </div> <div class="paper-actions"> <div class="paper-actions"> <button type="button" class="btn btn-success action-btn" data-bs-toggle="modal" data-bs-target="#claim_authorship"> <i class="fas fa-user-check"></i> Claim Authorship </button> </div> </div> <div class="paper-body"> <div class="abstract-section"> <abstract language="eng">The purpose of this study was to synthesize a water-soluble derivative of rutin (compound 2) by introducing carboxylate groups on rutin's sugar moiety. The rutin derivative showed an almost 100-fold solubility increase in water. The antiradical capacity of compound 2 was evaluated using the luminol/AAPH system, and the derivative's activity was 1.5 times greater than that of Trolox®. Despite the derivative's high solubility in water (log P = -1.13), lipid peroxidation of brain homogenate membranes was very efficiently inhibited (inhibition values were only 19% lower than the inhibition values of rutin). </div> <table class="info-table"> <tr> <th>Reference Key</th> <td> <div class="d-flex align-items-center flex-wrap"> <span class="badge bg-dark me-3">pedriali2008qumica<title</span> <span class="text-muted">Use this key to autocite in the manuscript while using <a href="https://scimatic.org" class="info-link" target="_blank">SciMatic Manuscript Manager or Thesis Manager</a> </span> </div> </td> </tr> <tr> <th>Authors</th> <td>;Carla Aparecida Pedriali;Adjaci Uchoa Fernandes;Leandra de Cássia Bernusso;Bronislaw Polakiewicz</td> </tr> <tr> <th>Journal</th> <td> <a href="https://journament.com/journal_stat/1013" class="info-link"> <i class="fas fa-book-open me-1"></i> greece and rome </a> </td> </tr> <tr> <th>Year</th> <td> 2008 </td> </tr> <tr> <th>DOI</th> <td> 10.1590/S0100-40422008000800039 </td> </tr> <tr> <th>URL</th> <td> <div class="mb-2"> <i class="fas fa-external-link-alt text-primary me-2"></i> <a href="http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422008000800039" target="_blank" class="info-link">http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422008000800039</a> </div> <div> <i class="fas fa-external-link-alt text-primary me-2"></i> <a href="https://doi.org/10.1590/S0100-40422008000800039" target="_blank" class="info-link">https://doi.org/10.1590/S0100-40422008000800039</a> </div> </td> </tr> <tr> <th>Keywords</th> <td> <span class="badge bg-danger">Keywords not found</span> </td> </tr> </table> </div> </div>   <div class="citations-section"> <div class="citations-header"> <h3 class="citations-title"> <i class="fas fa-quote-left"></i> Citations </h3> </div> <div class="citations-body"> <div class="empty-state"> <i class="fas fa-quote-right"></i> <p>No citations found. 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