pandemic influenza vaccines – the challenges

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ID: 150201
2009
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Abstract
Recent years’ enzootic spread of highly pathogenic H5N1 virus among poultry and the many lethal zoonoses in its wake has stimulated basic and applied pandemic vaccine research. The quest for an efficacious, affordable and timely accessible pandemic vaccine has been high on the agenda. When a variant H1N1 strain of swine origin emerged as a pandemic virus, it surprised many, as this subtype is well-known to man as a seasonal virus. This review will cover some difficult vaccine questions, such as the immunological challenges, the new production platforms, and the limited supply and global equity issues.
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Authors ;Rebecca Cox;Lars R. Haaheim;Abdullah S. Madhun
Journal International journal of pharmaceutics
Year 2009
DOI 10.3390/v1031089
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