in vitro assessment of optical properties of blood by applying the extended huygens-fresnel principle to time-domain optical coherence tomography signal at 1300 nm
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2008
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Abstract
A direct method for the measurement of the optical attenuation coefficient and the scattering anisotropy parameter based on applying the extended Huygens-Fresnel principle to optical coherence tomography images of blood is demonstrated. The images are acquired with a low-power probing beam at the wavelength of 1300 nm. Values of 12.15 mm−1 and 0.95 are found for the total attenuation coefficient and the scattering anisotropy factor, respectively. Also, as a preliminary step, the optical refraction index is determined with a precision of two decimal numbers directly from optical coherence images. The total attenuation coefficient and the scattering anisotropy factor are determined with precisions within experimental error margins of 5% and 2%, respectively. Readable OCT signal is obtained for a maximum propagation of light into blood of 0.25 mm. At the maximum probed depth, the measured signal is almost 103 smaller than its initial intensity when entering the sample.Reference Key |
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Authors | ;Dan P. Popescu;Michael G. Sowa |
Journal | Chemistry, an Asian journal |
Year | 2008 |
DOI | 10.1155/2008/591618 |
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