development of high performance liquid chromatography and mass spectrometry: a key engine of tcm modernization

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ID: 137909
2015
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Abstract
Traditional Chinese Medicine (TCM) has been popular for thousand years in prevention and treatment of chronic diseases synergistically with Western medicine while producing mild healing effects and lower side effects. Although many TCMs have been proven effective by modern pharmacological studies and clinical trials, their bioactive constituents and the remedial mechanisms are still not well understood. Researchers have made great efforts to explore the real theory of TCM for many years with different strategies. Development of high performance liquid chromatography (HPLC) and mass spectrometry within recent decade can provide scientists with robust technologies for disclosing the mysterious mask of TCM. In this paper, important innovations of HPLC and mass spectrometry are reviewed in the application of TCM analysis from single compound identification to metabolomic strategy.
Reference Key
zhang2015worlddevelopment Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Zheng-Xiang Zhang;Xue Qiao;Min Ye;Man-Yu Zhang;Yue Song;Tao Bo
Journal therapeutics and clinical risk management
Year 2015
DOI 10.15806/j.issn.2311-8571.2015.0006
URL
http://www.wjtcm.org:8080/ch/reader/create_pdf.aspx?file_no=20150006&year_id=2015&quarter_id=1&flag=1
Keywords
Mass spectrometry High performance liquid chromatography metabolomics active ingredients tcm quality controlmedicine (general)

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