Prospective study to determine clinical relevance of detection of pneumococcal DNA in sera of children by PCR

Clicks: 276
ID: 120865
1998
We undertook a prospective study to evaluate the accuracy of PCR of serum (aimed at the pneumococcal pneumolysin gene) at detecting pneumococcal infections in infants and children. The assay was positive for all blood and cerebrospinal fluid culture-positive samples and for 38 and 44% of patients wi …
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Authors Dagan R;Shriker O;Hazan I;Leibovitz E;Greenberg D;Schlaeffer F;Levy R;;
Journal Journal of clinical microbiology
Year 1998
DOI DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/9508293
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine adult age factors adolescent middle aged Child Infant Prospective Studies preschool DNA sensitivity and specificity pneumonia pneumococcal / diagnosis* evaluation studies as topic meningitis pneumococcal / microbiology streptococcus pneumoniae / genetics streptococcus pneumoniae / isolation & purification* bacteremia / microbiology pneumococcal infections / diagnosis* bacterial / blood* r dagan bacterial / genetics pneumococcal infections / microbiology bacterial proteins streptolysins / genetics nasopharynx / microbiology polymerase chain reaction* carrier state / microbiology bacteremia / diagnosis pmid:9508293 pmc104606 doi:10.1128/jcm.36.3.669-673.1998 o shriker r levy

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