Bioactive Lactones from the Mangrove-Derived Fungus Penicillium sp. TGM112.

Clicks: 221
ID: 119723
2019
Three new lactones penicilactones A-C (1-3) were obtained from the mangrove-derived fungus Penicillium sp. TGM112. Their structures and absolute configurations were determined by detailed NMR, MS spectroscopic data, Mo2(OAc)4-induced electronic circular dichroism (ECD), and circular dichroism (CD) spectroscopy. Compound 1 showed antibacterial activity against Staphylococcus aureus with an MIC value of 6.25 μg/mL. Compound 2 showed insecticidal activity against newly hatched larvae of Culex quinquefasciatus with the LC50 value of 78.5 (±0.58) μg/mL.
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Authors Meng Bai,Guo-Lei Huang,Rong-Qing Mei,Bin Wang,You-Ping Luo,Xu-Hua Nong,Guang-Ying Chen,Cai-Juan Zheng;Meng Bai;Guo-Lei Huang;Rong-Qing Mei;Bin Wang;You-Ping Luo;Xu-Hua Nong;Guang-Ying Chen;Cai-Juan Zheng;
Journal Marine drugs
Year 2019
DOI 10.3390/md17080433
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