Investigation into the selection frequency of resistant mutants and the bacterial kill rate by levofloxacin and ciprofloxacin in non-mucoid Pseudomonas aeruginosa isolates from cystic fibrosis patients

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ID: 119129
2002
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Abstract
The frequency by which resistant Pseudomonas aeruginosa strains could be selected was compared for two antibiotics, levofloxacin and ciprofloxacin. Seven distinct strains were cultured on plates containing 1x, 2x, 4x and 8x the minimum inhibitory concentration (MIC) of the antibiotic under investiga ā€¦
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Authors Gillespie T;Masterton RG;;
Journal international journal of antimicrobial agents
Year 2002
DOI DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/12007845
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine adult genetic* mutation drug resistance multiple bacterial* time factors microbial sensitivity tests pseudomonas aeruginosa / drug effects* dose-response relationship drug ciprofloxacin / pharmacology* levofloxacin* ofloxacin / pharmacology* pseudomonas infections / microbiology selection anti-infective agents / pharmacology t gillespie r g masterton pmid:12007845 doi:10.1016/s0924-8579(02)00017-1 cystic fibrosis / microbiology* pseudomonas aeruginosa / genetics

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