Beta-lactam antibiotic therapy in febrile granulocytopenic patients. A randomized trial comparing cefoperazone plus piperacillin, ceftazidime plus piperacillin, and imipenem alone

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ID: 118400
1991
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Abstract
Cefoperazone and ceftazidime were equally effective when used in combination antibiotic therapy with piperacillin. Twice-daily cefoperazone is less expensive than ceftazidime given three times daily. Monotherapy with imipenem, at a daily dose of 2 g, is as efficacious as double beta-lactam therapy a ā€¦
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Authors Winston DJ;Ho WG;Bruckner DA;Champlin RE;;
Journal annals of internal medicine
Year 1991
DOI DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/1952471
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't u.s. gov't adult female male adolescent aged middle aged Comparative Study P.H.S. Clinical Trial Randomized Controlled Trial anti-bacterial agents / adverse effects microbial sensitivity tests agranulocytosis / complications* drug therapy fever / drug therapy* r e champlin bacterial infections / drug therapy* combination / therapeutic use fever / etiology anti-bacterial agents / therapeutic use* costs and cost analysis anti-bacterial agents / economics bacterial infections / etiology fever / microbiology gram-negative bacterial infections / drug therapy gram-positive bacterial infections / drug therapy piperacillin / therapeutic use pmid:1952471 doi:10.7326/0003-4819-115-11-849 d j winston w g ho cefoperazone / therapeutic use ceftazidime / therapeutic use imipenem / therapeutic use superinfection / etiology

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