Boceprevir for untreated chronic HCV genotype 1 infection

Clicks: 345
ID: 117918
2011
The addition of boceprevir to standard therapy with peginterferon-ribavirin, as compared with standard therapy alone, significantly increased the rates of sustained virologic response in previously untreated adults with chronic HCV genotype 1 infection. The rates were similar with 24 weeks and 44 we …
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Authors Poordad F;McCone J;Bacon BR;Bruno S;Manns MP;Sulkowski MS;Jacobson IM;Reddy KR;Goodman ZD;Boparai N;DiNubile MJ;Sniukiene V;Brass CA;Albrecht JK;Bronowicki JP; ;;
Journal The New England journal of medicine
Year 2011
DOI DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/21449783
Keywords
hepatitis c National Center for Biotechnology Information NCBI NLM MEDLINE RNA humans pubmed abstract nih national institutes of health national library of medicine treatment outcome research support non-u.s. gov't adult female male middle aged Comparative Study Clinical Trial Phase III Randomized Controlled Trial Double-Blind Method Multicenter Study Genotype viral / blood drug therapy combination antiviral agents / therapeutic use* recombinant proteins viral load ribavirin / therapeutic use hepacivirus / isolation & purification chronic / virology african continental ancestry group antiviral agents / adverse effects hepacivirus / genetics* chronic / drug therapy* interferon alpha-2 serine proteinase inhibitors / adverse effects serine proteinase inhibitors / therapeutic use* pmid:21449783 pmc3766849 doi:10.1056/nejmoa1010494 fred poordad jonathan mccone sprint-2 investigators anemia / chemically induced chronic / ethnology interferon-alpha / therapeutic use polyethylene glycols / therapeutic use proline / adverse effects proline / analogs & derivatives* proline / therapeutic use

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