Safety and efficacy of lamivudine-zidovudine combination therapy in antiretroviral-naive patients. A randomized controlled comparison with zidovudine monotherapy. Lamivudine European HIV Working Group

Clicks: 345
ID: 117494
1996
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Abstract
The combination of lamivudine and zidovudine results in a potent and sustained antiviral effect in antiretroviral-naive patients that is superior to that observed with zidovudine monotherapy.
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Authors Katlama C;Ingrand D;Loveday C;Clumeck N;Mallolas J;Staszewski S;Johnson M;Hill AM;Pearce G;McDade H;;
Journal JAMA
Year 1996
DOI DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/8656503
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE RNA humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't adult female male middle aged Drug Administration Schedule Comparative Study Clinical Trial Randomized Controlled Trial Double-Blind Method Multicenter Study Genotype drug resistance viral / blood drug therapy combination antiviral agents / administration & dosage antiviral agents / therapeutic use* cd4 lymphocyte count microbial / genetics hiv infections / immunology hiv infections / drug therapy* pmid:8656503 c katlama d ingrand h mcdade hiv-1* / drug effects hiv-1* / genetics lamivudine reverse transcriptase inhibitors / administration & dosage reverse transcriptase inhibitors / therapeutic use* zalcitabine / administration & dosage zalcitabine / analogs & derivatives* zalcitabine / therapeutic use zidovudine / administration & dosage zidovudine / therapeutic use*

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