Malaria pigment paralyzes dendritic cells
Clicks: 218
ID: 116871
2006
The capacity of malarial infection to suppress the patient's immune responses both to the parasite and to other antigens has long puzzled researchers. A prime suspect, the parasite-produced pigment hemozoin, has now been clearly shown to mediate immunosuppression by inhibiting dendritic cell activit …
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bc2006journalmalaria
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| Authors | Urban BC;Todryk S;; |
| Journal | journal of biology |
| Year | 2006 |
| DOI | DOI not found |
| URL | |
| Keywords |
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
Mice
review
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
comment
malaria / immunology*
dendritic cells / immunology
pmid:16620370
pmc1561485
doi:10.1186/jbiol37
britta c urban
stephen todryk
dendritic cells / drug effects*
hemeproteins / metabolism
hemeproteins / pharmacology*
immune tolerance / drug effects
immunosuppressive agents / metabolism
immunosuppressive agents / pharmacology*
phagocytosis / drug effects
plasmodium / immunology
plasmodium / metabolism*
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