Insulin signaling displayed a differential tissue-specific response to low-dose dihydrotestosterone in female mice

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2018
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Abstract
Hyperandrogenemia and hyperinsulinemia are believed to play prominent roles in polycystic ovarian syndrome (PCOS). We explored the effects of low-dose dihydrotestosterone (DHT), a model of PCOS, on insulin signaling in metabolic and reproductive tissues in a female mouse model. Insulin resistance in ā€¦
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s2018americaninsulin Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Andrisse S;Billings K;Xue P;Wu S;;
Journal american journal of physiology endocrinology and metabolism
Year 2018
DOI DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/29351485
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Mice Inbred C57BL animals pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't female N.I.H. Extramural organ specificity / genetics dose-response relationship drug signal transduction / drug effects signal transduction / genetics pmid:29351485 pmc5966754 doi:10.1152/ajpendo.00195.2017 stanley andrisse katelyn billings sheng wu dihydrotestosterone / pharmacology* energy metabolism / drug effects hyperandrogenism / genetics hyperandrogenism / metabolism hyperandrogenism / pathology insulin / metabolism* insulin resistance / genetics muscle skeletal / drug effects skeletal / metabolism organ specificity / drug effects ovary / drug effects ovary / metabolism

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