Comparison of clindamycin, rifampin, tetracycline, metronidazole, and penicillin for efficacy in prevention of experimental gas gangrene due to Clostridium perfringens

Clicks: 326
ID: 115725
1987
Gas gangrene caused by Clostridium perfringens is associated with significant mortality and morbidity in spite of penicillin treatment. Although prompt surgical debridement has been established as the primary therapeutic objective, additional studies are needed for determination of the optimal antim …
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Authors Stevens DL;Maier KA;Laine BM;Mitten JE;;
Journal The Journal of infectious diseases
Year 1987
DOI DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/2879873
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Mice animals pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't u.s. gov't non-p.h.s. female male Comparative Study metronidazole / pharmacology clindamycin / therapeutic use anti-bacterial agents / pharmacology anti-bacterial agents / therapeutic use* metronidazole / therapeutic use* tetracycline / therapeutic use d l stevens pmid:2879873 doi:10.1093/infdis/155.2.220 k a maier j e mitten clindamycin / blood clindamycin / pharmacology clostridium perfringens / drug effects gas gangrene / prevention & control* metronidazole / blood penicillin g / blood penicillin g / pharmacology penicillin g / therapeutic use rifampin / blood rifampin / pharmacology rifampin / therapeutic use tetracycline / blood tetracycline / pharmacology

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