Usefulness of BCOR gene mutation as a prognostic factor in acute myeloid leukemia with intermediate cytogenetic prognosis

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ID: 114078
2018
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Abstract
BCOR gene is a transcription regulatory factor that plays an essential role in normal hematopoiesis. The wider introduction of next-generation sequencing technology has led to reports in recent years of mutations in the BCOR gene in acute myeloid leukemia (AML), but the related clinical characterist ā€¦
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Authors Terada K;Yamaguchi H;Ueki T;Usuki K;Kobayashi Y;Tajika K;Gomi S;Kurosawa S;Saito R;Furuta Y;Miyadera K;Tokura T;Marumo A;Omori I;Sakaguchi M;Fujiwara Y;Yui S;Ryotokuji T;Arai K;Kitano T;Wakita S;Fukuda T;Inokuchi K;;
Journal genes, chromosomes & cancer
Year 2018
DOI DOI not found
URL
https://www.pubmed.gov/29663558/
Keywords
leukemia National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine prognosis female male aged middle aged hiroki yamaguchi survival rate koiti inokuchi myeloid acute / genetics* acute / pathology genetic predisposition to disease mutation* pmid:29663558 doi:10.1002/gcc.22542 kazuki terada cytogenetic analysis / methods high-throughput nucleotide sequencing acute / metabolism proto-oncogene proteins / genetics* repressor proteins / genetics* fms-like tyrosine kinase 3 / genetics

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