Cytotoxic and Anti-Inflammatory Effects of Ent-Kaurane Derivatives Isolated from the Alpine Plant Sideritis hyssopifolia
Clicks: 179
ID: 113772
2020
This paper reports the isolation and structural characterization of four new ent-kaurane derivatives from the Lamiaceae plant Sideritis hyssopifolia. Planar structures and relative configurations were determined using both mass spectrometry and nuclear magnetic resonance (1D and 2D). Absolute configurations were determined by comparing experimental and theoretical electronic circular dichroism spectra. The cytotoxic and microbial activities of all new compounds were tested. Compounds that were non-cytotoxic were further evaluated for anti-inflammatory activity.
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aimond2020moleculescytotoxic
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| Authors | Axelle Aimond;Kevin Calabro;Coralie Audoin;Elodie Olivier;Mélody Dutot;Pauline Buron;Patrice Rat;Olivier Laprévote;Soizic Prado;Emmanuel Roulland;Olivier P. Thomas;Grégory Genta-Jouve;Aimond, Axelle;Calabro, Kevin;Audoin, Coralie;Olivier, Elodie;Dutot, Mélody;Buron, Pauline;Rat, Patrice;Laprévote, Olivier;Prado, Soizic;Roulland, Emmanuel;Thomas, Olivier P.;Genta-Jouve, Grégory; |
| Journal | molecules |
| Year | 2020 |
| DOI | 10.3390/molecules25030589 |
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