Episomal Segregation of the Adenovirus Enhancer Sequence by Conditional Genome Rearrangement Abrogates Late Viral Gene Expression

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Abstract
We have constructed a recombinant adenovirus gene delivery system that is capable of undergoing growth phase-dependent site-specific recombination. When propagated in 293 producer cells, the vector retains its linear double-stranded form and can be propagated ...
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Authors Xinzhong Wang, Weike Zeng, Masahiro Murakawa, Mason W. Freeman, Brian Seed;Xinzhong Wang;Weike Zeng;Masahiro Murakawa;Mason W. Freeman;Brian Seed;
Journal Journal of Virology
Year 2000
DOI 10.1128/jvi.74.23.11296-11303.2000
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