Changes in plasma human immunodeficiency virus type 1 RNA associated with herpes simplex virus reactivation and suppression

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ID: 112816
2002
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Abstract
In early trials of antiretroviral therapy, acyclovir was associated with increased survival by an unknown mechanism. The hypothesis that subclinical herpes simplex virus (HSV) reactivation was associated, in vivo, with increased plasma human immunodeficiency virus (HIV) RNA and suppression with a re ā€¦
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Authors Schacker T;Zeh J;Hu H;Shaughnessy M;Corey L;;
Journal The Journal of infectious diseases
Year 2002
DOI DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/12447756
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE RNA humans pubmed abstract nih national institutes of health national library of medicine research support u.s. gov't adult female male middle aged Comparative Study P.H.S. Clinical Trial Viral / analysis follow-up studies time factors antiviral agents / administration & dosage antiviral agents / therapeutic use* cd4 lymphocyte count hiv infections / complications herpesvirus 2 human / isolation & purification virus shedding pmid:12447756 doi:10.1086/345771 timothy schacker judith zeh lawrence corey acyclovir / administration & dosage acyclovir / therapeutic use* hiv antibodies / blood hiv infections / blood hiv infections / virology* hiv-1 / isolation & purification* herpes genitalis / blood herpes genitalis / complications herpes genitalis / virology herpes simplex / blood herpes simplex / complications herpes simplex / virology* simplexvirus / drug effects simplexvirus / isolation & purification* simplexvirus / physiology virus activation / drug effects*

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