Bioactive Lactones from the Mangrove-Derived Fungus Penicillium sp. TGM112
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ID: 112027
2019
Three new lactones penicilactones A−C (1−3) were obtained from the mangrove-derived fungus Penicillium sp. TGM112. Their structures and absolute configurations were determined by detailed NMR, MS spectroscopic data, Mo2(OAc)4-induced electronic circular dichroism (ECD), and circular dichroism (CD) spectroscopy. Compound 1 showed antibacterial activity against Staphylococcus aureus with an MIC value of 6.25 μg/mL. Compound 2 showed insecticidal activity against newly hatched larvae of Culex quinquefasciatus with the LC50 value of 78.5 (±0.58) μg/mL.
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bai2019marinebioactive
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| Authors | Meng Bai;Guo-Lei Huang;Rong-Qing Mei;Bin Wang;You-Ping Luo;Xu-Hua Nong;Guang-Ying Chen;Cai-Juan Zheng;Bai, Meng;Huang, Guo-Lei;Mei, Rong-Qing;Wang, Bin;Luo, You-Ping;Nong, Xu-Hua;Chen, Guang-Ying;Zheng, Cai-Juan; |
| Journal | Marine drugs |
| Year | 2019 |
| DOI | 10.3390/md17080433 |
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