NICOTINE-BORANE BASED TASK-SPECIFIC IONIC LIQUID AS AS ALTERNATIVE REAGENT TO PYRIDINE-BORANE FOR EFFICIENT REDUCTIVE AMINATION

Abstract

Nicotine-based task specific ionic liquid has been used as a carrier of boron hydride instead of pyridine borane and other related reagents. Borohydride complex of Nicotine-IL has been used for reductive amination of variety of carbonyls and amines with encouraging results. The same reagent has the potential of other applications. The reactions were conducted under pyridine free odorless conditions. The improved results were obtained in terms of enhanced yields, with minimal work up.